This can be easily achieved early on using Isaac as bosses give HP upgrades more often than not (especially before other items are unlocked). To unlock Magdalene you must have seven or more red heart containers on a character in one run. Magdalene is the second character of the game. You will also unlock the following items that are not tied to specific achievements but still count towards Real Platinum God -ДЇor beating Mom's Heart on Hard Mode - Lost Baby (co-op character)ДЇor beating Greed Mode - Lil' Chest (Afterbirth)ДЇor beating Greedier Mode - D1 (Afterbirth+)ДЇor beating Hush - Fart Baby (Afterbirth)ДЇor beating Mega Satan - Cry Baby (Afterbirth, co-op character)ДЇor beating Delirium - D Infinity (Afterbirth+)ДЇor getting all Hard Mode checks on post-it note - Buddy Baby (Afterbirth, co-op character) - Can be done in Afterbirth prior to getting Afterbirth+ When/if you change the D6 out for another item is up to you and is a judgement call you will learn to make as you go through the game.ДЄs you make progress through the game with Isaac you will unlock the following achievements and items. Whenever you find items in the item room, shop, after beating a boss, or in a devil/angel that you don't like, you can use the D6 to re-roll the items to hopefully get something better. With the D6 in hand, you want to hold onto it for a while as you make your way through the floors. Once you unlock the D6, Isaac will always start with it giving him a slightly different playstyle. Isaac is the most basic character with all his stats starting out reasonably decent and in the beginning there is little to no specific strategy involved when playing as him. With all that explained let's get onto the characters themselves. From Afterbirth onward, you must get each mark checked off with its hard mode version to unlock all secrets for the corresponding achievements. To add the red version, you must clear that boss/bonus area on Hard (Greedier mode for the bottom-center mark). Delirium (Causes the post-it note to become crinkled/bloodied around the edges)Дefeating each of the above will put the corresponding image on that characters post-it note.Greed Mode (Greedier Mode for red mark in Afterbirth+).From top to bottom, left to right the symbols represent which bosses/bonus areas the character has defeated which are.

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